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Hematological cancer, commonly referred to as blood cancer, is a form of cancer that originates in the organs responsible for blood production, such as the bone marrow or lymphatic system. It disrupts the production or function of blood cells and can occur when cancer impacts the bone marrow, a spongy tissue inside the bones, or the small lymph nodes that help fight infections (lymph nodes). Doctors use different ways to fight it. Older methods include chemotherapy, which uses strong medicines to kill cancer cells, and radiation therapy, which uses powerful beams to target specific areas. Another method is stem cell transplantation, where unhealthy blood-making cells are replaced with healthy ones, which can sometimes cure the cancer. More recently, new treatments have been developed. Immunotherapies help your own body's defense system (immune system) fight cancer. The treatment that's best for someone depends on the exact type of blood cancer they have, how advanced it is, and their overall health. Scientists are constantly working to improve these treatments and find new ones that work better and have fewer side effects for people with blood cancer. This review discusses the mechanism, application and benefits of therapies for blood cancer treatment